The LMP8645 and the LMP8645HV devices are precision current sense amplifiers that detect small differential voltages across a sense resistor in the presence of high-input common-mode voltages. Operating from a supply range of 2.7 V to 12 V, the LMP8645 accepts input signals with a common-mode voltage range of –2 V to 42 V, while the LMP8645HV accepts input signals with a common-mode voltage range of –2 V to 76 V. The LMP8645 and LMP8645HV have adjustable gain for applications where supply current and high common-mode voltage are the determining factors. The gain is configured with a single resistor, providing a high level of flexibility, as well as accuracy as low as 2% (maximum) including the gain setting resistor. The output is buffered to provide low output impedance. This high-side current sense amplifier is ideal for sensing and monitoring currents in DC or batterypowered systems, has excellent AC and DC specifications over temperature, and keeps errors in the current sense loop to a minimum. The LMP8645 is an ideal choice for industrial, automotive, and consumer applications, and is available in SOT-6 package.